Search results for "Comorbidity score"

showing 2 items of 2 documents

Chemotherapy of metastatic colon cancer in France: A population-based study

2021

International audience; Aims: to describe, using data from a cancer registry in a well-defined French population, the therapeutic strategies and survival of patients with metastatic colon cancer (mCC).Methods: all patients with synchronous mCC diagnosed within the 2005-2014 period recorded in the digestive cancers registry of Burgundy were included.Results: 1286 mCC patients were included (57% male), of which 34.5% did not receive any antitumor treatment. Both, advanced age (≥75 years) and the Charlson comorbidity score ≥2 were significantly associated with the absence of antitumor treatment. Among the patients treated with chemotherapy, 59 and 33% received at least two and three lines, res…

Malemedicine.medical_specialtyOrganoplatinum Compounds[SDV]Life Sciences [q-bio]medicine.medical_treatmentPopulationLeucovorinAdenocarcinomaPopulation-basedTargeted therapy03 medical and health sciences0302 clinical medicineInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansChemotherapyIn patientRegistrieseducationAgedRetrospective StudiesMetastatic colon cancerChemotherapyeducation.field_of_studyHepatologyMetastatic colorectal cancerbusiness.industryPalliative CareComorbidity scoreAge FactorsGastroenterologyMiddle Aged3. Good healthCancer registry[SDV] Life Sciences [q-bio]Population based study030220 oncology & carcinogenesisColonic NeoplasmsCamptothecinFemale030211 gastroenterology & hepatologyFluorouracilFrancebusiness
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Comorbidities, Fragility, and Quality of Life in Heart Failure Patients With Midrange Ejection Fraction.

2018

Objective: To assess the effects of comorbidities, fragility, and quality of life (QOL) on long-term prognosis in ambulatory patients with heart failure (HF) with midrange left ventricular ejection fraction (HFmrEF), an unexplored area. Patients and Methods: Consecutive patients prospectively evaluated at an HF clinic between August 1, 2001, and December 31, 2015, were retrospectively analyzed on the basis of left ventricular ejection fraction category. We compared patients with HFmrEF (n=185) to those with reduced (HFrEF; n=1058) and preserved (HFpEF; n=162) ejection fraction. Fragility was defined as 1 or more abnormal evaluations on 4 standardized geriatric scales (Barthel Index, Older A…

medicine.medical_specialtylcsh:R5-920Ejection fractionbusiness.industryDepression scaleComorbidity score030204 cardiovascular system & hematologymedicine.disease03 medical and health sciences0302 clinical medicineFragilityQuality of lifeHeart failureInternal medicineAmbulatoryCardiologyMedicineGeriatric Depression Scale030212 general & internal medicinebusinesslcsh:Medicine (General)Mayo Clinic proceedings. Innovations, qualityoutcomes
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